General

This article advocates for a holistic, interdisciplinary approach to brain health, integrating neurology, psychiatry, and environmental factors under the "One Health" and "Planetary Health" frameworks. It highlights the rising global burden of brain disorders, which impact at least one in three people and cost Europe over $1 trillion annually. Environmental factors like air pollution and climate change significantly influence cognitive decline, while social determinants also shape neurological health. The Swiss Brain Health Plan (SBHP) serves as a model for integrating research, policy, and patient empowerment. The authors stress the need for systemic solutions and global collaboration to enhance brain health strategies.

This review explores lifestyle factors affecting longevity and cognitive health. It emphasizes the role of physical activity, diet, stress management, sleep, and social connections in extending lifespan. Regular exercise reduces mortality risk, while plant-based diets and specific phytochemicals may delay aging. Alcohol and smoking negatively impact longevity. The review also discusses emerging anti-aging drugs but notes their unproven long-term safety. The study is a literature review, meaning it does not include direct participant data, a control group, or randomization. Its findings synthesize existing research, making it informative but not independently generalizable.

This study explores how uncertainty affects people recently diagnosed with relapsing-remitting multiple sclerosis (RRMS). Through in-depth interviews, researchers found that patients experience uncertainty as a state between hope and grief, influenced by bodily changes, shifting self-perception, and evolving social relationships. The unpredictability of MS symptoms leads to heightened anxiety, difficulty making decisions, and fear of the future. Understanding this uncertainty can help healthcare providers offer more personalized support and guidance, improving emotional resilience and coping strategies.

This study presents a deep learning-based system for diagnosing Multiple Sclerosis (MS) using MRI scans. The researchers developed a Content-Based Medical Image Retrieval (CBMIR) system leveraging Convolutional Neural Networks (CNNs) and Transfer Learning (TL) with the Inception V3 model trained on RadImageNet. The model was fine-tuned using Bayesian optimization and evaluated across four public MS MRI datasets. The system demonstrated high retrieval accuracy (mAP scores: 86.2%–94.18%), with potential for aiding radiologists in MS diagnosis.

The article "Top 10 studies on lifestyle choices for managing MS" from Overcoming MS highlights recent research emphasizing the significant role of lifestyle modifications in managing multiple sclerosis (MS). These studies provide evidence on how factors such as diet, exercise, stress management, and holistic care can influence disease progression and overall well-being. The curated list serves as a resource for individuals seeking to understand the impact of lifestyle behaviors on MS and offers insights for discussions with healthcare professionals.

This study aimed to establish internationally applicable lifestyle recommendations and behavior change strategies to promote brain health for individuals with multiple sclerosis (MS). Using a modified Delphi process, experts from healthcare and individuals with lived experience of MS developed consensus on strategies such as physical activity, smoking cessation, mental health support, and diet. The frameworks emphasize multidisciplinary approaches and aim to close the gap between knowledge and action. This research underscores the importance of adopting a brain-healthy lifestyle to improve cognition, mitigate disease progression, and enhance quality of life for MS patients.

This study examined the baseline engagement of people with multiple sclerosis (MS) with six healthy lifestyle behaviors—diet, vitamin D supplementation, omega-3 intake, physical activity, meditation, and nonsmoking—and their impact on health outcomes. Findings revealed that engaging with at least four healthy behaviors correlated with higher quality of life (QoL), reduced fatigue, and lower disability prevalence. Diet and physical activity emerged as key contributors to mental and physical QoL improvements. The research underscores the potential of multimodal lifestyle interventions to enhance health outcomes in MS management.

This study examined how engaging in healthy lifestyle behaviors impacts quality of life (QoL) over 7.5 years in people with multiple sclerosis (MS). Behaviors analyzed included a healthy diet, physical activity, meditation, smoking abstinence, and vitamin D supplementation. Findings revealed that a healthy diet and regular physical activity were consistently associated with improved mental and physical QoL. Engaging in three or more behaviors provided the most significant QoL benefits, suggesting a cumulative effect. This highlights the importance of multimodal lifestyle interventions in MS management for sustained cognitive and physical health.