One Brain, One Mind, One Health, One Planet—A Call from Switzerland for a Systemic Approach in Brain Health Research, Policy and Practice

This article advocates for a holistic, interdisciplinary approach to brain health, integrating neurology, psychiatry, and environmental factors under the "One Health" and "Planetary Health" frameworks. It highlights the rising global burden of brain disorders, which impact at least one in three people and cost Europe over $1 trillion annually. Environmental factors like air pollution and climate change significantly influence cognitive decline, while social determinants also shape neurological health. The Swiss Brain Health Plan (SBHP) serves as a model for integrating research, policy, and patient empowerment. The authors stress the need for systemic solutions and global collaboration to enhance brain health strategies.