White matter plasticity in healthy older adults: The effects of aerobic exercise

This study assessed how aerobic exercise impacts white matter health in older adults over six months. Participants engaged in walking, dancing, or active control exercises, with walking and dancing showing improved white matter integrity (T1w/T2w signal) compared to declines in the control group. Enhanced white matter integrity in late-myelinating areas, like the corpus callosum, correlated with improved episodic memory, suggesting neuroplasticity persists in aging brains. The findings indicate aerobic exercise can slow age-related brain decline, benefiting memory and overall cognitive health.

Older adults should incorporate regular aerobic activities, such as walking or dance, into their routines. Aim for moderate-intensity sessions three times per week for about 40 minutes each. The research demonstrates measurable brain health benefits, though individual outcomes may vary. Effects on white matter support improved memory and long-term cognitive health, but replication in larger, more diverse populations is necessary to confirm generalizability.