The Impact of High-Intensity Interval Training on Brain Derived Neurotrophic Factor in Brain: A Mini-Review

This mini-review highlights how high-intensity interval training (HIIT) enhances brain-derived neurotrophic factor (BDNF) levels, a protein critical for brain plasticity, memory, and learning. HIIT involves short bursts of intense exercise, which elicit higher BDNF increases than traditional moderate exercise. In both animal and human studies, HIIT boosted BDNF in the brain, supporting neuronal growth and metabolic health. These findings underscore HIIT's potential for cognitive improvement and brain health, especially in combating stress and aging-related decline.

Incorporate HIIT into your exercise routine to boost brain health. Perform 20–30 minutes of HIIT, such as sprinting or cycling at 80–100% of maximum effort, interspersed with recovery periods. This may enhance BDNF levels, supporting memory and cognitive function. While promising, these findings are based on preliminary human data and extensive animal studies. Consult a professional before starting HIIT, especially if you have health concerns or are new to intense exercise.