RESOURCE
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January 20, 2019

Physical Activity and Brain Health

Research
Genes
SUMMARY

This research highlights the positive impact of physical activity (PA) on brain health, emphasizing how movement fosters cognitive function, combats aging, and mitigates neurodegenerative diseases like Alzheimer's. PA promotes the release of neurotrophic factors like BDNF and other molecules from muscles, which enhance neuroplasticity, memory, and mood regulation. Mechanisms include increased neurogenesis, mitochondrial biogenesis, and epigenetic regulation. The findings affirm the ancient principle of "a sound mind in a sound body," linking exercise to lifelong cognitive vitality.

RECOMMENDATION

Engage in regular, moderate-intensity aerobic and resistance exercises, such as brisk walking or strength training, for at least 150 minutes weekly. Tailor activity to personal ability and health, as findings support exercise’s universal benefits on cognitive health and neuroprotection. Note the research relies on correlational and mechanistic evidence, suggesting robust applicability, though individual responses may vary.

TAGS
physical activity; brain health; bdnf; neurogenesis; neuroplasticity; exercise; epigenetics; aging; neurodegeneration; cognition
DEEP DIVE