Grip strength performance from 9431 participants of the GenoFit study: normative data and associated factors

This study analyzed grip strength in 9,431 adults (18–92 years) as part of the GenoFit study to establish normative data and assess associations with health variables. The study found that grip strength is strongly linked to lean mass, cardiorespiratory fitness, bone density, and disease prevalence (p < 0.001). A control group was used for comparison, and statistical analyses adjusted for confounders. The study's large sample size improves generalizability, though its cross-sectional design limits causal inference. Results suggest grip strength is a valuable screening tool for aging-related health risks, supporting early intervention strategies.

To maintain grip strength and overall brain health, engage in resistance training and aerobic exercise, as both are linked to muscle retention and cognitive function. Prioritize protein intake to support muscle synthesis. While this study reinforces grip strength’s predictive value for health, it does not establish causation. Broader interventions beyond muscle strength, such as social engagement and mental stimulation, remain essential.