Exercise-Related Physical Activity Relates to Brain Volumes in 10,125 Individuals

This study investigated how moderate-to-vigorous physical activity impacts brain structure in a sample of over 10,000 participants using MRI. Regular exercise was linked to increased brain volumes in regions such as the hippocampus, frontal lobe, and gray and white matter—key areas for memory, learning, and cognitive function. The findings suggest that even lower levels of physical activity than typically recommended can enhance brain health, supporting neuroprotection against aging and neurodegenerative diseases. While self-reported physical activity and a cross-sectional design limit causality, the results align with existing evidence connecting exercise to improved cognitive and structural brain health.

Engage in regular moderate physical activity, such as brisk walking or cycling, for at least 150 minutes weekly. This study found that even lower levels of activity significantly benefit brain health, increasing brain volume and potentially reducing the risk of cognitive decline. While causality cannot be fully established due to study limitations, these findings reinforce the importance of consistent movement for long-term brain health and resilience.