The National Institutes of Health's Office of Dietary Supplements provides a comprehensive overview of valerian (Valeriana officinalis), an herb commonly used as a dietary supplement in the United States. Valerian is often included in products marketed as mild sedatives and sleep aids for conditions like nervous tension and insomnia. However, clinical studies on its effectiveness for sleep disorders have yielded inconclusive results. While certain constituents of valerian exhibit sedative effects in animal studies, the precise mechanisms of action in humans remain unclear. Notably, few adverse events have been reported with valerian use, but data on its long-term safety are lacking.Regarding brain health and cognitive performance, the potential sedative properties of valerian might aid individuals experiencing sleep disturbances, thereby indirectly supporting cognitive functions that depend on adequate rest. However, due to the inconclusive evidence of its efficacy and the absence of long-term safety data, it is advisable to consult healthcare professionals before incorporating valerian supplements into one's regimen. This recommendation aligns with the cautious stance presented in the NIH fact sheet, underscoring the importance of personalized medical advice.