Unravelling the health effects of fasting: a long road from obesity treatment to healthy life span increase and improved cognition

This review discusses the health benefits of fasting on lifespan, metabolism, and brain health. Fasting promotes a shift from glucose to ketones as an energy source, reducing inflammation and enhancing cellular repair processes like autophagy. It improves brain function through better energy metabolism, increased neuroplasticity, and reduced oxidative stress. Various fasting methods, including intermittent and prolonged fasting, show promise for preventing neurodegenerative diseases and improving cognition. Human and animal studies support its potential but highlight the need for tailored approaches.

Incorporate a fasting strategy such as time-restricted eating (e.g., an 8-hour daily eating window) to support brain health and longevity. Pair fasting with a nutrient-rich diet. Consult a healthcare provider for a personalized plan, especially if managing health conditions, as fasting protocols need to be tailored to individual needs.