The role of probiotics and prebiotics in modulating of the gut-brain axis

This review explores how probiotics and prebiotics impact the gut-brain axis and support mental health by influencing gut microbiota composition. These compounds may reduce symptoms of depression, anxiety, Alzheimer’s disease, and stress by enhancing neurotransmitter production, reducing neuroinflammation, and improving gut barrier integrity. Mechanisms include short-chain fatty acid production and modulation of the hypothalamic-pituitary-adrenal axis. Although animal and some human studies show promise, evidence remains preliminary, and larger trials are needed to confirm therapeutic effects.

Add probiotic-rich foods (e.g., yogurt, kefir) and prebiotic sources (e.g., onions, bananas) to your diet to support mental health and cognitive resilience. Probiotics and prebiotics may help by balancing gut microbiota, reducing inflammation, and enhancing brain function. While evidence suggests benefits for conditions like anxiety and Alzheimer’s, most findings are early-stage or derived from animal studies. Consult a healthcare provider before using these as part of treatment for mental health conditions.