The Relationship of Ketogenic Diet with Neurodegenerative and Psychiatric Diseases: A Scoping Review from Basic Research to Clinical Practice

This scoping review discusses the ketogenic diet (KD) and its effects on neurodegenerative and psychiatric conditions such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, autism, and depression. KD promotes brain health by reducing inflammation, oxidative stress, and amyloid plaques while enhancing mitochondrial function, neuronal repair, and gut microbiome diversity. While basic research and animal studies show promising results, clinical evidence is limited due to small sample sizes, short durations, and lack of controls in human studies.

Consider a medically supervised ketogenic diet for potential neuroprotective benefits. It may support cognitive health and manage symptoms of neurological conditions. However, further research is needed to confirm long-term safety and efficacy, and it is essential to ensure balanced nutrient intake.