The Health-Promoting Effects and the Mechanism of Intermittent Fasting

This review discusses the health benefits and mechanisms of intermittent fasting (IF) for conditions like obesity, diabetes, cancer, neurological diseases, and aging. IF promotes metabolic flexibility, reduces inflammation, and enhances cellular repair processes like autophagy. It also supports brain health by improving mitochondrial function and boosting neuroplasticity through pathways like BDNF signaling. Preliminary human studies and animal research suggest IF's potential to improve cognition and prevent neurodegenerative diseases, but further long-term studies are needed.

Adopt an intermittent fasting schedule, such as the 16:8 method, to enhance brain health, metabolic function, and longevity. Pair fasting with a balanced diet rich in whole foods. Consult a healthcare provider to personalize fasting regimens, especially if managing chronic conditions, as more human research is needed to confirm safety and effectiveness.