RESOURCE
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January 20, 2017

The Emerging Role for Zinc in Depression and Psychosis

Research
Frontiers in Pharmacology
SUMMARY

This review highlights the role of zinc in brain function and its potential to address psychiatric disorders like depression and psychosis. Zinc deficiency, linked to stress, poor diet, or genetic factors, can disrupt neurotransmission and neuroplasticity. Zinc supplementation has shown promise as an adjunctive treatment for depression, enhancing the effects of antidepressants, and may help modulate psychotic symptoms by regulating NMDA receptor activity. These findings suggest zinc’s importance in maintaining mental health and as a possible therapeutic tool.

RECOMMENDATION

To support brain health, include zinc-rich foods like nuts, seeds, lean meats, and legumes in your diet. Consider zinc supplements only under medical advice, as they may complement traditional treatments for conditions like depression. Further research is needed to clarify dosage and long-term benefits in diverse populations.

TAGS
zinc; depression; psychosis; neurotransmission; NMDA receptors; neuroplasticity; supplementation; mental health; psychiatric disorders; neuroprotection
DEEP DIVE