RESOURCE
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January 20, 2019

Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer’s Disease and Parkinson’s Disease)

Research
Nutrients
SUMMARY

This review examines the role of ketogenic diets (KDs) in managing Alzheimer’s and Parkinson’s diseases. By shifting energy metabolism to ketones, KD reduces oxidative stress, improves mitochondrial function, and decreases neuroinflammation, all contributing to better brain health. Evidence from animal studies and limited human trials shows KD can improve motor and cognitive symptoms, reduce amyloid-beta plaques in Alzheimer’s, and enhance dopamine production in Parkinson’s. However, adherence challenges and potential long-term risks require further investigation.

RECOMMENDATION

A ketogenic diet may support brain health and help manage neurodegenerative symptoms. Consult a healthcare provider to determine if KD is suitable for you, considering individual health conditions and nutritional needs. Ensure sufficient protein intake to mitigate risks like muscle loss.

TAGS
ketogenic diet; neurodegenerative diseases; Alzheimer’s disease; Parkinson’s disease; mitochondria; oxidative stress; amyloid-beta; neuroinflammation; cognitive function; dopamine production
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