Relationship between Serum and Brain Carotenoids, α-Tocopherol, and Retinol Concentrations and Cognitive Performance in the Oldest Old from the Georgia Centenarian Study

This study investigated the link between blood and brain levels of dietary antioxidants, like carotenoids (lutein, zeaxanthin, β-carotene), and cognitive performance in very old adults, including centenarians. It found that higher levels of certain carotenoids, particularly lutein and β-carotene, were associated with better cognitive performance and less dementia severity. Brain carotenoid concentrations mirrored serum levels, suggesting diet influences brain health. The study highlights the potential role of diets rich in green leafy vegetables and colorful fruits in preserving cognitive function as we age.

Incorporate more green leafy vegetables (rich in lutein) and colorful fruits and vegetables like carrots and sweet potatoes (high in β-carotene) into your diet. These may support brain health and slow cognitive decline, especially in older age. The findings are significant but based on cross-sectional data; they suggest dietary improvements but don't prove causation.