Psychological Stress and Mitochondria: A Systematic Review

This systematic review explores how psychological stress impacts mitochondria, the cellular "powerhouses." It finds that chronic stress disrupts mitochondrial function, including energy production and cellular signaling, leading to conditions like oxidative stress and inflammation. These effects are linked to impaired brain function, emotional health, and systemic diseases. While animal studies dominate the findings, they suggest a relationship between stress and mitochondrial damage. Limited human studies imply similar trends but need better methods to confirm causality and depth.

To protect mitochondria under stress, adopt regular physical activity, mindfulness meditation, or a balanced diet rich in antioxidants. These strategies can support mitochondrial health by reducing oxidative stress and inflammation. Given the robust evidence from animal studies and emerging human research, such practices are likely beneficial but should complement professional health advice for managing chronic stress.