Probiotics Treatment Can Improve Cognition in Patients with Mild Cognitive Impairment: A Systematic Review

This systematic review analyzed five randomized controlled trials on the effects of probiotics on mild cognitive impairment (MCI). Probiotic interventions using strains like Lactobacillus and Bifidobacterium over 12-16 weeks showed improvements in cognitive domains such as memory, attention, and mental flexibility. Benefits were most pronounced in individuals with MCI and not in those with advanced dementia or normal cognition. Probiotics appear to act through the gut-brain axis, reducing neuroinflammation and increasing brain-derived neurotrophic factor (BDNF). These findings support probiotics as a potential preventive measure for cognitive decline, though further research is needed.

Consider adding probiotic-rich foods (e.g., yogurt, kefir) or supplements containing Lactobacillus and Bifidobacterium strains to your diet. These probiotics may support cognitive health by reducing neuroinflammation and enhancing gut-brain communication. Benefits are more likely in those with mild cognitive impairment rather than advanced conditions. Consult a healthcare provider before starting probiotics, especially if you have specific health conditions or are taking other medications.