Microbiota shaping — the effects of probiotics, prebiotics, and fecal microbiota transplant on cognitive functions: A systematic review

This systematic review explores the effects of probiotics, prebiotics, and fecal microbiota transplant (FMT) on cognitive function through gut microbiota manipulation. The evidence indicates that probiotics and FMT improve cognition by reducing neuroinflammation and promoting gut-brain axis health. Probiotics enhanced cognitive function in healthy individuals and patients with conditions like Alzheimer’s disease and mild cognitive impairment. Prebiotics showed limited cognitive benefits, possibly due to short treatment durations. The findings highlight gut microbiota's role in brain health but emphasize the need for larger, long-term studies to confirm efficacy.

Incorporate probiotic-rich foods (e.g., yogurt, kefir) into your diet to support brain health by enhancing gut-brain axis function. For targeted benefits, consider probiotic supplements containing strains like Lactobacillus and Bifidobacterium. This review supports cognitive benefits, particularly in aging or neurodegenerative conditions, but findings are mixed, and long-term effects remain uncertain. Prebiotic intake (e.g., fiber from vegetables) can complement these efforts. Consult a healthcare provider for tailored guidance.