Intermittent Fasting Enhanced the Cognitive Function in Older Adults with Mild Cognitive Impairment by Inducing Biochemical and Metabolic changes: A 3-Year Progressive Study

This three-year study investigated the effects of intermittent fasting (IF) on cognitive function in older adults with mild cognitive impairment (MCI). Regular IF significantly improved cognitive scores, reduced oxidative stress, inflammation, and DNA damage, while enhancing antioxidant levels and metabolic health. Participants practicing IF regularly had better cognitive recovery, with 24.3% achieving successful aging compared to 3.7% of non-fasters. These findings suggest that IF may promote brain health by modulating key biochemical and metabolic pathways.

Adopt intermittent fasting, such as fasting two non-consecutive days a week, to support cognitive health and reduce MCI progression. Pair with a balanced diet to ensure nutritional adequacy. Consult a healthcare provider before starting, especially if managing chronic conditions, as results may vary across individuals.