RESOURCE
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January 12, 2025

Intermittent fasting and neurocognitive disorders: What the evidence shows

Research
The Journal of Nutrition, Health and Aging
SUMMARY

Intermittent fasting (IF) may support brain health and combat neurocognitive disorders like Alzheimer’s and vascular cognitive impairment. By increasing brain-derived neurotrophic factor (BDNF) and promoting neurogenesis, IF enhances learning, memory, and brain resilience. It also reduces neuroinflammation and oxidative stress, which are linked to cognitive decline. Human studies, though limited, show promise in mild cognitive impairment, indicating improved cognition and metabolic health. While animal studies are robust, more research is needed to standardize and confirm IF's therapeutic benefits for humans.

RECOMMENDATION

Incorporate intermittent fasting (e.g., 16-hour daily fasts or alternate-day fasting) into your routine to promote brain health and reduce inflammation. Pair this with a balanced diet rich in fruits, vegetables, and healthy fats for optimal results. However, consult a healthcare provider, especially if you have pre-existing conditions or take medications. The research, while promising, is limited in human applicability and long-term effects.

TAGS
intermittent fasting, neurocognition, brain health, neuroplasticity, inflammation, Alzheimer’s disease, cognitive decline, mild cognitive impairment, BDNF, CREB, neurogenesis, oxidative stress, time-restricted eating, dementia, lifestyle intervention
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