This study investigated the combined effects of GABA and l-theanine on sleep quality using animal models. The mixture significantly reduced the time it took to fall asleep and increased both REM and non-REM sleep duration compared to GABA or l-theanine alone. The combination improved brain wave patterns associated with restful sleep and enhanced expression of sleep-related receptors. These findings suggest that GABA and l-theanine together may have a synergistic effect on improving sleep, potentially benefiting cognitive function and mental well-being by supporting restorative sleep.
A combination supplement of GABA and l-theanine may improve sleep latency and quality, especially for those with sleep disturbances. However, consult a healthcare provider before starting supplements. Findings are based on animal studies, so further research in humans is needed to confirm efficacy and determine optimal dosing.