Effects of Intermittent Fasting on Brain Metabolism

This review explores the impact of intermittent fasting (IF) on brain metabolism and cognitive health. IF promotes a shift from glucose to ketones as the brain's energy source during fasting, enhancing stress resistance, synaptic plasticity, and neurogenesis. Key molecular changes include increased brain-derived neurotrophic factor (BDNF), improved mitochondrial function, and reduced inflammation. Preliminary animal and human studies show improved memory, reduced neurodegeneration, and potential benefits for conditions like Alzheimer's and epilepsy. However, more research is needed for clinical guidelines.

Consider intermittent fasting methods like time-restricted eating (e.g., 16-hour fast, 8-hour eating window) to support brain health. Pair with a balanced diet for best results. Consult a healthcare provider to ensure safety, especially if managing chronic conditions.