RESOURCE
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June 10, 2020

Brain macroautophagy on the ketogenic diet

Research
Proceedings of the Nutrition Society
SUMMARY

This study investigated the ketogenic diet's (KD) ability to stimulate autophagy in the brain, a process crucial for clearing cellular waste and maintaining brain health. Using mouse models, researchers found that KD increased autophagosome levels, particularly in the hippocampus and frontal cortex, suggesting enhanced brain cell repair and protection. This mechanism may explain KD's neuroprotective benefits in managing conditions like epilepsy and potentially slowing brain aging and neurodegeneration. These findings advance our understanding of KD's impact on brain health.

RECOMMENDATION

Consider a ketogenic diet to support brain health, particularly if facing conditions like epilepsy or seeking preventive measures for cognitive decline. However, KD should be supervised by a healthcare provider, as its long-term effects and suitability vary among individuals.

TAGS
ketogenic diet; autophagy; neuroprotection; brain health; hippocampus; frontal cortex; neurodegeneration; epilepsy; cellular repair; aging
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