Assessment of a multi-ingredient dietary supplement on sleep quality: a randomized, double-blinded, placebo-controlled crossover clinical study

This study investigated a multi-ingredient dietary supplement’s effect on sleep quality in individuals with insomnia. Thirty adults participated in a 6-week, randomized, double-blind, placebo-controlled crossover study. The supplement, containing colostrum, egg yolk extracts, ashwagandha, lavender oil, melatonin, GABA, and magnesium, significantly improved difficulty falling asleep and reduced nighttime awakenings (p < 0.01). Salivary melatonin levels increased significantly in the treatment group. However, limitations included a small sample size, placebo effects, and a lack of physiological sleep data from gold-standard measures like polysomnography. Findings suggest the supplement may aid sleep but require further validation.

To improve brain health, individuals can prioritize sleep hygiene by maintaining a consistent sleep schedule, reducing blue light exposure before bed, and incorporating relaxation techniques such as meditation. While the supplement in the study showed promise, its efficacy remains uncertain due to the small sample size and self-reported measures. Nutrient-rich diets, regular exercise, and stress management may provide more broadly validated cognitive benefits.