Appraising the brain's energy budget

This commentary discusses the brain's substantial energy demands, which consume about 20% of the body's oxygen despite its small size. Most energy is used for synaptic activity, maintaining balance between excitatory and inhibitory processes, essential for cognitive function and connectivity. Transient metabolic changes during brain activation, like those detected by imaging, are minor compared to the baseline metabolic activity. This highlights the brain's continuous high-energy requirements for maintaining functional readiness and adaptability.

To support brain health, ensure a diet rich in energy-providing nutrients like complex carbohydrates and omega-3 fatty acids. Regular physical activity and proper sleep can optimize glucose metabolism and synaptic function. These lifestyle choices complement the brain's high metabolic demands and enhance cognitive performance.